주요논문
Aryl Sulfate is a Useful Motif for Conjugating and Releasing Phenolic Molecules :
Sulfur Fluorine Exchange Click Chemistry Enables Discovery of Ortho-Hydroxy-Protected Aryl Sulfate Linker.
Bioconjugate Chem.
2019, 30, 7, 1957–1968
Introduction of Para-Hydroxy Benzyl Spacer Greatly Expands the Utility of Ortho-Hydroxy-Protected Aryl Sulfate System :
Application to Nonphenolic Payloads
Bioconjugate Chem.
2019, 30, 7, 1969–1978
Sulfonate Version of OHPAS Linker Has Two Distinct Pathways of Breakdown :
Elimination Route Allows Para-Hydroxy-Protected Benzylsulfonate (PHP-BS) to Serve as an Alternative Self-Immolative Group
Bioconjugate Chem.
2020, 31, 5, 1392–1399
Assessments of the In Vitro and In Vivo Linker Stability and Catabolic Fate for the Ortho Hydroxy-Protected Aryl Sulfate Linker by Immuno-Affinity Capture Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometric Assay
Pharmaceutics.
2021, 13 (1), 125
ITC-6102RO, a novel B7-H3 antibody-drug conjugate, exhibits potent therapeutic effects against B7-H3 expressing solid tumors
Cancer Cell International.
2023, 23 : 172